Lesch-Nyhan syndrome causes compulsive self-mutilation. Children eat their lips or fingers, and stab their faces with sharp objects. They feel the pain, but they cannot stop themselves. Why would a loving, all-powerful creator allow anyone to be born with such an awful disease?
Lesch-Nyhan is just one of the tens of thousands of genetic disorders discovered so far. At least a tenth of people have some kind of debilitating genetic disease, and most of us will become sick at some point during our lifetime as a result of mutations that cause diseases such as cancer.
The reason? Our genome is an unmitigated mess. The replication and repair mechanisms are inadequate, making mutations commonplace. The genome is infested with parasitic DNA that often wreaks havoc. The convoluted control mechanisms are prone to error. The huge amount of junk, not just between genes but within them, wastes resources. And some crucial bits of DNA are kept in the power factories - mitochondria - where they are exposed to mutagenic byproducts. "It is downright ludicrous!" declares John Avise, an evolutionary geneticist at the University of California, Irvine.
The human genome, Avise concludes, offers no shred of comfort for those seeking evidence of a loving, all-powerful creator who had a direct hand in designing us, as not just creationists but many believers who accept evolution think was the case. If some entity did meddle with life on Earth, it either did not know what it was doing or did not care, or both.
Thursday, 18 February 2010
Our genome is an unmitigated mess
Interesting book review in New Scientist of which the following is an extract. Read this and tell me you still believe in an omnipotent creator...